Mice are often used to test whether substances in food are harmful to humans. This requires that mice and humans metabolize substances in the same way. This may not be perfectly true (after all mice and men are different). The health risk associated with harmful substances in food may therefore be underestimated. Researchers at the Norwegian Institute of Public Health have adopted a mouse type where human enzymes have been inserted to examine whether people may be more sensitive to certain carcinogenic substances from heat-treated foods. They have obtained a better model to assess negative health effects in humans from substances in food using these mice.

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Of Mice and Men

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